Wheatgrass molecules ( PV ) Ai Report.docx

Review each suggested relationship below. Accept it if it looks right, edit it to fix a mistake, or reject it if it is wrong. Only accepted relationships will appear on the knowledge map. Rows marked "requires review" are not deleted or blocked - they are just flagged for a closer look.

Subject	Relationship	Object	Evidence	Evidence Stance	AI Extraction Confidence	Status
5-Fluorouracil Drug	is associated with	angioneurotic edema Outcome	the patient developed angioneurotic edema/angioedema during continuous infusion 5-FU after prior courses the patient developed angioneurotic edema/angioedema during continuous infusion 5-FU after prior courses	Supports	95% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	oral mucositis Outcome	Oral mucous membrane disorders in 69.2% intra-arterial arm Oral mucous membrane disorders in 69.2% intra-arterial arm	Supports	92% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	neutropenia Outcome	milder neutropenia systemically milder neutropenia systemically	Supports	90% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	myelotoxicity Outcome	the main toxicities were myelotoxicity, nausea, and vomiting the main toxicities were myelotoxicity, nausea, and vomiting	Supports	90% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	nausea Outcome	the main toxicities were myelotoxicity, nausea, and vomiting the main toxicities were myelotoxicity, nausea, and vomiting	Supports	92% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	vomiting Outcome	the main toxicities were myelotoxicity, nausea, and vomiting the main toxicities were myelotoxicity, nausea, and vomiting	Supports	92% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	facial palsy Outcome	facial palsy complication occurred in one patient facial palsy complication occurred in one patient	Supports	88% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	leukopenia Outcome	Main adverse effects were leukopenia and mucositis Main adverse effects were leukopenia and mucositis	Supports	90% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	mucositis Outcome	Main adverse effects were leukopenia and mucositis Main adverse effects were leukopenia and mucositis	Supports	92% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	thrombocytopenia Outcome	Thrombocytopenia, anorexia, nausea, vomiting, stomatitis, SIADH Thrombocytopenia, anorexia, nausea, vomiting, stomatitis, SIADH	Supports	88% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	anorexia Outcome	Thrombocytopenia, anorexia, nausea, vomiting, stomatitis, SIADH Thrombocytopenia, anorexia, nausea, vomiting, stomatitis, SIADH	Supports	88% Claim basis	Accepted
5-Fluorouracil Drug	is associated with	stomatitis Outcome	Thrombocytopenia, anorexia, nausea, vomiting, stomatitis, SIADH Thrombocytopenia, anorexia, nausea, vomiting, stomatitis, SIADH	Supports	90% Claim basis	Accepted
5-Fluorouracil Drug	treats	oral cancer Disease	all oral carcinoma patients achieved CR all oral carcinoma patients achieved CR	Supports	85% Claim basis	Accepted
5-Fluorouracil Drug	was tested in Scientific relationship requires review Expected pattern: Molecule/Drug -> TESTED_IN -> ExperimentalModel	oral cancer Disease	26 oral-cancer patients total, 13 per arm 26 oral-cancer patients total, 13 per arm	Supports	95% Claim basis	Pending
Chlorophyllin Molecule	inhibits	NF-κB signaling pathway Pathway	Inhibited NF-κB and induced intrinsic apoptosis in hamster buccal pouch carcinogenesis Inhibited NF-κB and induced intrinsic apoptosis in hamster buccal pouch carcinogenesis	Supports	90% Claim basis	Accepted
Chlorophyllin Molecule	was tested in	hamster model of oral oncogenesis ExperimentalModel	Dietary chlorophyllin inhibits the canonical NF-κB signaling pathway and induces intrinsic apoptosis in a hamster model of oral oncogenesis Dietary chlorophyllin inhibits the canonical NF-κB signaling pathway and induces intrinsic apoptosis in a hamster model of oral oncogenesis	Supports	95% Claim basis	Accepted
Quercetin Molecule	inhibits	CYP3A4 Protein	Quercetin can inhibit CYP3A4, CYP2C19, OATPs, BCRP, and MRP2 Quercetin can inhibit CYP3A4, CYP2C19, OATPs, BCRP, and MRP2	Supports	92% Claim basis	Accepted
Quercetin Molecule	inhibits	CYP2C19 Protein	Quercetin can inhibit CYP3A4, CYP2C19, OATPs, BCRP, and MRP2 Quercetin can inhibit CYP3A4, CYP2C19, OATPs, BCRP, and MRP2	Supports	92% Claim basis	Accepted

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